Dr. Denese Triple Strength Wrinkle Smoother Advanced Treatment 3.4 oz – Night Cream with Triple Amount of Peptides vs Industry Standards – Retinol & Hyaluronic Acid Hydrating Power – Paraben Free

Price: $52.02

(as of Feb 25, 2026 07:01:13 UTC –

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Product description

Comparison Table

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Customer Reviews

4.5 out of 5 stars 68

4.6 out of 5 stars 865

4.6 out of 5 stars 1,029

4.7 out of 5 stars 469

4.3 out of 5 stars 56

4.6 out of 5 stars 211

5.0 out of 5 stars 1

Price

$52.02$52.02

$110.00$110.00

$49.00$49.00

$39.00$39.00

$39.00$39.00

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Formula Strength

Triple peptide smoothing

Retinol, ceramide, peptide mix

AHA exfoliant with peptides

Hydration Tech + Peptides

Peptide-botanical firming mix

SPF40 + antioxidant boost

Retinol–glycolic retinoate mix

Application

Apply AM/PM to target areas

AM or PM after cleansing

Use daily or as tolerated

AM/PM – massage until absorbed

Roll on AM/PM until abosorbed

Apply AM; reapply as needed

Use nightly; avoid eyes

Best For

Wrinkles and uneven texture

Dry to very dry skin

Aging, textured, dull skin

Dry, dehydrated, lined skin

Neck laxity and early lines

Tinted SPF for uneven skin

Dull, uneven, aging texture

Benefit

Deep line–smoothing formula

Hydrates and restores lipids

Exfoliates and refines tone

Deep hydration for supple skin

Firms for a lifted neck look

Light coverage with UV defense

Overnight resurfacing care

Skin Concerns

Deep lines, texture, firmness

Dryness and loss of firmness

Pores, uneven tone, fine lines

Dry patches and dullness

Neck laxity, crepe, fullness

Sun damage and uneven tone

Dullness and uneven texture

Texture

Rich cream with smoothing feel

Light serum with soft finish

Pre-soaked one-step pad

Rich adaptive non-greasy cream

Light roll-on gel serum

Light BB cream with tint

Pre-soaked quick-dry peel pad

Key Ingredients

Peptide-retinol-lipid blend

Retinol, ceramides, peptides

Glycolic acid + peptides + C

Ceramides, Retinol, Peptides

Peptides + botanical firmers

SPF40 + antioxidants + niacin

Glycolic + retinoate blend

Visible Results

Reduced lines in weeks

Visibly smoother, plumper look

Smoother, brighter look

Hydrated smoother-looking skin

Firmer, smoother neck look

Instantly evens; improves look

Smoother skin in weeks

Shelf Life

24m sealed, 6–9m after open

24m sealed, 6–12m after open

24m sealed, 6–9m after open

24m sealed, 6–12m after open

24m sealed, 6–9m after open

24m sealed, 6–12m after open

24m sealed, 6–9m after open

Does it help with forehead wrinkles and fine lines?

Yes. This night cream targets forehead lines, fine lines, and deep wrinkles with a triple-strength peptide complex and gentle AHAs to help visibly firm, smooth, and refine mature skin over time.

Can it be used on sensitive or mature skin?

This wrinkle cream for face works well for most skin types, including mature skin. It’s paraben-free and enriched with chamomile and allantoin to calm, hydrate, and visibly improve skin texture. Patch test if sensitive.

Can I use this moisturizer every night?

Yes. Use this night moisturizer for face as the last step in your skincare routine. Start 2–3 nights a week, then build to nightly use for smoother, firmer-looking, well-hydrated skin while you sleep.

Can it be applied to the neck area too?

Absolutely. This firming face and neck cream combines peptides and AHAs to help smooth, tighten, and hydrate skin, improving the look of firmness and elasticity from chin to décolleté.

Is it cruelty-free and paraben-free?

Yes. This clean, skin-firming moisturizer for women and men is cruelty-free, paraben-free, sulfate-free, and phthalate-free—crafted for visible results with a gentle, skin-friendly formula.

Is Discontinued By Manufacturer ‏ : ‎ No
Package Dimensions ‏ : ‎ 6.42 x 4.76 x 2.72 inches; 3.4 ounces
UPC ‏ : ‎ 811684021911
Manufacturer ‏ : ‎ Dr. Denese
ASIN ‏ : ‎ B07DFL6KFR
Best Sellers Rank: #104,440 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #311 in Facial Night Creams
Customer Reviews: 4.5 4.5 out of 5 stars (68) var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
TRIPLE PEPTIDE COMPLEX FOR SMOOTHER SKIN: Formulated with advanced peptides, glycerin, and squalane to visibly refine lines and wrinkles while restoring hydration for a firmer, more even look that feels supple, smooth, and revitalized every night.
HYDRATING NIGHT CREAM FOR FACE: Luxurious texture delivers lasting moisture and comfort, leaving skin refreshed and resilient. Designed for visible firmness and elasticity, this nightly moisturizer supports smoother tone and renewed softness.
VISIBLE RESULTS THAT BUILD CONFIDENCE: Consistent nightly use helps reveal refined texture and a smoother surface. This face cream supports hydrated, balanced skin that feels firmer and more resilient without heaviness or greasy residue.
CLEAN, CRUELTY-FREE FORMULA: Crafted without parabens, sulfates, or phthalates. Dermatologist-developed and cruelty-free, this formula embodies Dr. Denese’s commitment to effective skincare rooted in science, integrity, and performance.
TRUSTED SKINCARE INNOVATION: From the award-winning Dr. Denese SkinScience line, this peptide moisturizer blends proven actives with luxurious care, offering a balanced approach to visible wrinkle smoothing and long-lasting hydration.